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Xickle RBC-Plus: The Next Generation of Niprisan

January 19, 2015 by Andrea

Remember Niprisan, the drug that was approved for the treatment of sickle cell in Nigeria? See the results from the Niprisan clinical trial in the graph below. Well, Xickle RBC-Plus is the new generation of Niprisan. Currently sold in its supplement form, Xickle RBC-Plus has shown that it can help prevent the red blood cells of sickle cell patients from sickling. Clinical trials are currently underway.

Niprasan vs Control

Before preparing for our human clinical trials, we tested Xickle RBC-Plus on mice with human sickle cell disease. The mice that were given Xickle RBC-Plus lived longer, healthier lives than the mice who were not given the supplement. Take a look at the photo below to see just how our supplement helped maintain the shape of the red blood cells in the treated mice.

Mice RBCs

This next image, shows the same supplement at work of the blood from a person with sickle cell disease. The cells on the left were taken from a sickle cell patient and put under low oxygen conditions, as expected, they sickled. The cells on the right were also drawn from a sickle cell patient and subjected to low oxygen conditions, but this time, Xickle RBC-Plus was added to the blood. As you can see, it helped keep them from becoming sickled.


In the next few weeks and months, we'll be presenting you with more updates about our clinical trial and its progress. Meanwhile, stay up to date by following us on Facebook and Twitter. Have any questions? Comment below or Tweet us @XickleRBC!

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